The scale and scope of the COVID-19 pandemic have reiterated the need for access to and analysis of timely accurate health data to support the implementation of control measures and to guide health interventions and evidence-based practices. The supporting infrastructures and capacities through which researchers access and analyze these data, however, vary greatly. For several reasons, researchers in the Global South often are skeptical of broad calls for data sharing when they are left out of the analysis and results interpretation.