Launched in 2012, Grand Challenges Brazil is a partnership framework for the Ministry of Health of Brazil, its National Council on Research (CNPq), the Bill & Melinda Gates Foundation and other funders to launch joint challenges aimed at catalyzing innovative health research within Brazil. The partnership includes co-funding of Grand Challenges Explorations grants in Brazil by the Brazilian state-based research foundations (FAPs). Explore awarded grants and watch videos from the 2013 Grand Challenges meeting in Rio de Janeiro.