Product/Service Development

The proposed solution aims to develop an application for optical scanning of the Mother and Child Protection (MCP) card immunization record for use by frontline workers equipped with a mobile smartphone. Real-time point-of-service data entry will leapfrog the existing MCTS/ RCH approach based on data entry at the Primary Health Centre (PHC) to improve data accuracy, timeliness and completeness

The projects aims to reconcile coverage (from ANMOL / CAS) and consumption data (from eVIN) using blockchain technology to create a robust, scalable, real-time tracking and triangulation system on immunization data in India.

The study focuses on the transmission dynamics of resistance in poultry farm workers to estimate the possibility of zoonotic transfer of pathogens. The study will be looking at humans, animals, air and water as well

The study plans to collect stool samples from children admitted to the ICU to identify invasive MDR Enterobacteriaceae. Serial sampling of these children and subsequently their family members in the community will allow for longitudinal study of the microbiome and the presence of carbapenemase bacterial genes in their faecal samples. This will allow assessment of the risk of secondary transmission of hospital acquired resistant strains to household contacts

The project proposes to monitor AMR at metagenomic level by focusing on unique microbial antibiotic resistance genes (ARG) signatures and tracking the resistance from the "source" to the "sink". The approach intends to provide direct information about AMR and its implications on vulnerable populations. This information is lacking in Indian context and a reliable catalogue would help in proper visualization of the network involved in AMR and to develop strategies to mitigate it

The study intends to implement an ecological multi-host surveillance to document the bacterial infections and antibacterial resistance (ABR) among humans, animals, birds and fishes sharing the environment and linkage with antibiotics and disinfectant exposures at individual, household/habitation and community levels from different sources. A multi-host and multi-species approach shall improve understanding on pattern and spread of bacterial infection and resistance considering the "One Health" perspective.

The project intends to create a Raman database by collecting and recording Raman spectra at every step of various bacterial strains that are sensitive, intermediate or resistant to antimicrobial agents. The focus is to understand the progression/emergence of AMR to work as a supportive surveillance technology. The spectral database will also aid in prediction of possible resistance in bacterial strains. we aim to evaluate how bio spectroscopy, in particular Raman spectroscopy, can be utilised to fingerprint microbiomes and study the progression of AMR resistance in bacteria

In current situation, both conventional and advanced wastewater treatment technologies are either inefficient or costly for removal of micro-pollutants drug particles, heavy metals etc. from water. While, existing membranes have been reported to be not compatible for re-use and recycle. These gaps demonstrate that there is still apparent requirement of a cost-effective simpler solution for providing people with quality water. In the previous study, the study team have efficiently utilized Sericin to remove a model drug Ibuprofen from aqueous solution.

The project proposes use of metabolomics including High throughput Nuclear Magnetic Resonance (NMR) spectroscopy and Liquid-chromatography mass spectrometry (LC-MS) as a powerful tool for the discovery of biomarkers for differentiating bacteremic cases and non-bacteremic cases among febrile neutropenic Cancer patients to decrease antibiotic consumption, differentiating antimicrobial resistance extended spectrum beta-lactamase (ESBL) present or not based on metabolites and differentiating community acquired blood stream infections and hospital acquired blood stream infections including Centr

The study intends to develop new low-cost technology based on ferroelectric materials bulk, powder coating/thick film to impair the life of microbial cells commonly found in drinking tap water, water storage tanks and nosocomial infections. Organic pollutant like pharmaceutical waste would be another target area. Remnant charges present on ferroelectric materials surfaces due to dipole polarization of materials are responsible for water micro electrolysis which results in reactive oxygen species (ROS). Microbial cells are susceptible to high ROS content.